• Upstream/Downstream Process Development Research Associate

    Posted Date 3 weeks ago(10/24/2018 1:15 PM)
    Job ID
    2018-3229
    # of Openings
    1
    Job Location(s)
    US-MD-Bethesda
    Category
    Research
  • Overview

    Medical Science & Computing (MSC) is an exciting growth oriented company, dedicated to providing mission critical scientific and technical services to the Federal Government. We have a distinguished history of supporting the National Institutes of Health (NIH) and other government agencies. MSC offers a dynamic and upbeat work environment, excellent benefits and career growth opportunities.

     

    We attract the best people in the business with our competitive benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, Medical and Flexible Spending Accounts, Pre-Tax Transit Assistance and tuition reimbursement. If you enjoy being a part of a high performing, professional service and technology focused organization, please apply today!

     

    Duties & Responsibilities

    Medical Science & Computing is searching for an Upstream/Downstream Process Development Research Associate to support the National Institutes of Health (NIH). This opportunity is a full-time position with MSC and is on-site in Bethesda, MD.

     

    The applicant will report to the Head of Process Development and CMC Unit and will be responsible for the following:

    • Support vaccine development initiatives, including the production of vaccines for Phase 1 and 2 vaccine trials.
    • Involved in the development of scalable fermentation and purification processes for production of recombinant malaria antigens produced by Escherichia coli or Pichia pastoris.
    • Small-scale and pilot-scale (60L) fermentation development
    • Analysis of approaches for harvesting, purification development of scalable procedures
    • Support to the analytical effort
    • Other duties include preparing various media, buffers, stock supplies, and other reagents for use in the laboratory

    Requirements

    • BS in molecular biology, biochemistry or related field and three or more years of related experience, or a MS in a similar field with one or more years of related experience. 
    • Knowledge of current Good Laboratory Practices and current Good Manufacturing Practices
    • Knowledge of FDA drug approval process
    • Experience preparing laboratory protocols
    • Experience with vaccine research and development preferred
    • Experience using New Brunswick fermenters, Akta Explorers and/or Pilot, or equivalent equipment is essential. 
    • Experience with Western blotting procedures, endotoxin testing and other HPLC/UPLC methods would be an advantage.  
    • Strong computer skills including experience with Microsoft Word, PowerPoint, Excel and graphics programs.
    • Excellent verbal and written communication skills.

    Medical Science & Computing is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status.

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